Christian T Ruff Selected Research

Factor Xa (Coagulation Factor Xa)

1/2022	Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex.
4/2021	Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation with warfarin or edoxaban: An in-depth analysis from the ENGAGE AF-TIMI 48 randomized trial.
1/2021	Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients With Cardiometabolic Disease.
1/2021	Comparison of the Efficacy and Safety Outcomes of Edoxaban in 8040 Women Versus 13 065 Men With Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial.
1/2021	Randomized, Double-Blind Comparison of Half-Dose Versus Full-Dose Edoxaban in 14,014 Patients With Atrial Fibrillation.
1/2021	Edoxaban versus warfarin in patients with atrial fibrillation in relation to the risk of stroke: A secondary analysis of the ENGAGE AF-TIMI 48 study.
11/2020	Cardiovascular- and Bleeding-Related Hospitalization Rates With Edoxaban Versus Warfarin in Patients With Atrial Fibrillation Based on Results of the ENGAGE AF-TIMI 48 Trial.
12/2019	Left atrial structure and function and the risk of death or heart failure in atrial fibrillation.
11/2019	Comparison of Events Across Bleeding Scales in the ENGAGE AF-TIMI 48 Trial.
1/2019	Clinical outcomes, edoxaban concentration, and anti-factor Xa activity of Asian patients with atrial fibrillation compared with non-Asians in the ENGAGE AF-TIMI 48 trial.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Christian T Ruff Research Topics

Disease

65	Atrial Fibrillation 09/2022 - 09/2010
52	Stroke (Strokes) 09/2022 - 09/2010
50	Hemorrhage 09/2022 - 03/2012
43	Myocardial Infarction 03/2022 - 11/2007
23	Embolism (Embolus) 09/2022 - 10/2010
11	Ischemic Stroke 11/2020 - 03/2014
10	Heart Failure 07/2022 - 05/2008
10	Acute Coronary Syndrome 01/2020 - 01/2006
9	Cardiovascular Diseases (Cardiovascular Disease) 03/2022 - 11/2011
8	Coronary Artery Disease (Coronary Atherosclerosis) 12/2021 - 01/2006
8	Thromboembolism 01/2021 - 09/2010
8	Thrombosis (Thrombus) 11/2019 - 01/2006
6	Type 2 Diabetes Mellitus (MODY) 07/2022 - 11/2018
6	Body Weight (Weight, Body) 01/2022 - 01/2016
6	Intracranial Hemorrhages (Intracranial Hemorrhage) 04/2021 - 01/2016
5	Hypertension (High Blood Pressure) 01/2021 - 06/2011
5	Diabetes Mellitus 01/2021 - 01/2020
5	Venous Thromboembolism 10/2020 - 09/2010
4	Hemorrhagic Stroke 01/2021 - 08/2014
4	Transient Ischemic Attack 11/2020 - 08/2014
3	Genetic Risk Score 01/2020 - 10/2019
3	Weight Loss (Weight Reduction) 01/2019 - 01/2018
3	Overweight 01/2019 - 01/2018
3	Infections 01/2019 - 04/2002
3	Chest Pain (Chest Pains) 04/2014 - 09/2013
2	Atherosclerosis 03/2022 - 04/2014
2	Neoplasms (Cancer) 01/2022 - 01/2018
2	Chronic Renal Insufficiency 01/2021 - 01/2019
2	Vascular Diseases (Vascular Disease) 11/2018 - 01/2014
2	Heart Valve Diseases (Valvular Heart Disease) 11/2018 - 03/2017
1	Peripheral Arterial Disease 09/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 04/2021
1	Subdural Hematoma (Subdural Hemorrhage) 04/2021
1	Inflammation (Inflammations) 01/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2020

Drug/Important Bio-Agent (IBA)

58	Warfarin (Coumadin)FDA LinkGeneric 09/2022 - 09/2010
51	edoxabanIBA 09/2022 - 10/2010
31	Factor Xa (Coagulation Factor Xa)IBA 01/2022 - 10/2010
27	AnticoagulantsIBA 01/2022 - 01/2006
17	Vitamin K FDA Link 01/2022 - 10/2010
9	Factor Xa InhibitorsIBA 03/2019 - 10/2010
8	CreatinineIBA 01/2022 - 06/2011
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 05/2008
6	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 01/2014
5	N(4)-oleylcytosine arabinosideIBA 01/2021 - 08/2014
5	Pharmaceutical PreparationsIBA 11/2020 - 06/2015
5	Clopidogrel (Plavix)FDA Link 11/2018 - 06/2009
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 03/2022 - 01/2014
3	oxidized low density lipoproteinIBA 03/2022 - 04/2014
3	evolocumabIBA 01/2022 - 01/2020
3	C-Reactive ProteinIBA 01/2021 - 05/2008
3	TroponinIBA 01/2021 - 03/2013
3	pro-brain natriuretic peptide (1-76)IBA 01/2021 - 06/2011
3	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2021 - 05/2008
3	Proprotein Convertase 9IBA 10/2020 - 01/2020
3	5-HT2C Serotonin ReceptorIBA 01/2019 - 01/2018
3	lorcaserinIBA 01/2019 - 01/2018
3	dapagliflozinIBA 01/2019 - 01/2019
3	Troponin IIBA 04/2014 - 05/2008
3	Prasugrel Hydrochloride FDA Link 03/2012 - 06/2009
2	CholesterolIBA 01/2022 - 01/2020
2	RivaroxabanIBA 01/2022 - 01/2020
2	Growth Differentiation Factor 15IBA 01/2021 - 01/2019
2	saxagliptin FDA Link 01/2021 - 01/2021
2	TicagrelorIBA 01/2021 - 01/2021
2	LDL CholesterolIBA 01/2020 - 10/2019
2	Enoxaparin (Lovenox)FDA LinkGeneric 01/2020 - 11/2007
2	LDL Lipoproteins (beta Lipoproteins)IBA 10/2019 - 04/2014
2	omega-Chloroacetophenone (Mace)IBA 01/2019 - 01/2019
2	Hemoglobins (Hemoglobin)IBA 01/2019 - 01/2018
2	Sodium-Glucose Transport ProteinsIBA 01/2019 - 01/2019
2	Peroxidase (Myeloperoxidase)IBA 03/2013 - 05/2008
1	Sitagliptin Phosphate (Januvia)FDA Link 07/2022
1	Lipoproteins (Lipoprotein)IBA 03/2022
1	LipidsIBA 03/2022
1	ApolipoproteinsIBA 03/2022
1	Apolipoproteins B (ApoB)IBA 03/2022
1	VLDL LipoproteinsIBA 03/2022
1	Exenatide (Byetta)FDA Link 01/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	Apolipoproteins E (ApoE)IBA 01/2022
1	apixabanIBA 01/2022
1	Lipase (Acid Lipase)FDA Link 12/2021
1	Natriuretic PeptidesIBA 01/2021
1	Troponin T (Troponin T1)IBA 01/2021
1	darapladibIBA 01/2021
1	SmokeIBA 01/2021
1	fibrin fragment D (D-dimer)IBA 01/2021
1	alirocumabIBA 01/2020
1	betrixabanIBA 01/2020

Therapy/Procedure

19	Therapeutics 03/2022 - 06/2009
5	Drug Tapering 07/2016 - 01/2015
2	Patient Readmission 01/2020 - 05/2008
2	Stents 03/2012 - 01/2012
2	Percutaneous Coronary Intervention 01/2012 - 06/2009
1	Subcutaneous Infusions 01/2022
1	Contraindications 01/2021
1	Length of Stay 01/2020